Document ID (ISN) | 27026 |
CIS number |
77-739 |
ISSN - Serial title |
0041-008X - Toxicology and Applied Pharmacology |
Year |
1976 |
Convention or series no. |
|
Author(s) |
Young J.D., Braun W.H., Gehring P.J., Horvath B.S., Daniel R.L. |
Title |
1,4-dioxane and β-hydroxyethoxyacetic acid excretion in urine of humans exposed to dioxane vapors. |
Bibliographic information |
Dec. 1976, Vol.38, No.3, p.643-646. 8 ref. |
Abstract |
An average of 3.5µM/l 1,4-dioxane and 414µM/l β-hydroxyethoxyacetic acid (HEAA) daily were found in the urine of dioxane plant personnel exposed to 1.6ppm dioxane. The biotransformation of dioxane is thus similar to that found in rats. The high ratio of HEAA to dioxane suggests that dioxane is rapidly metabolised, and that exposure to low concentrations of dioxane vapour presents a neglible hazard. |
Descriptors (primary) |
chemical industry; metabolic process; urinary metabolites; toxicology; dioxane |
Descriptors (secondary) |
human experiments |
Document type |
- |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Ethers Chemical industry
|