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CISDOC database
| Document ID (ISN) | 26845 |
| CIS number |
77-468 |
| ISSN - Serial title |
0003-4878 - Annals of Occupational Hygiene |
| Year |
1976 |
| Convention or series no. |
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| Author(s) |
Bouley G., Dubreuil A., Godin J., Boisset M., Boudène C. |
| Title |
Phenomena of adaptation in rats continuously exposed to low concentrations of acrolein. |
| Bibliographic information |
July 1976, Vol.19, No.1, p.27-32. 27 ref. |
| Abstract |
Rats exposed to 0.55ppm acrolein had significantly lower body weight, relative liver weight and serum acid phosphatase levels than controls, irritation of the upper respiratory tract, reduced alveolar macrophages, and a higher susceptibility to airborne Salmonella infection, after 11-21 days' exposure. After 63 days' exposure, however, all differences between exposed animals and controls had disappeared, except for continued significant differences in body weight. Adaptation appeared to set in after 3-4 weeks' exposure. |
| Descriptors (primary) |
toxicology; acrolein; adaptation to intoxication |
| Descriptors (secondary) |
body weight; animal experiments |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
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| Broad subject area(s) |
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| Browse category(ies) |
Aldehydes
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