| Document ID (ISN) | 26281 |
| CIS number |
76-2032 |
| Year |
1975 |
| Convention or series no. |
|
| Author(s) |
Smith A.H., Tappan D.V.
Naval Submarine Medical Research Lab, Groton, Connecticut. |
| Title |
Erythrocyte fragility changes resulting from short exposures to 6.7 ATA compressed air. |
| Bibliographic information |
AD-A021 775/2WJ, National Technical Information Service, Springfield, Virginia 22151, USA, 2 Dec. 1975. 14p. 21 ref. Price: Photocopy US-$3.50/Microfiche US-$2.25. |
| Abstract |
Analyses were made of osmotic fragility changes in human erthrocytes occurring as a result of 40-45min exposures to 6.7 ATA of compressed air with subsequent decompression. The cells exhibited a decreased fragility at 1h after completion of the simulated dives; mean fragility subsequently increased for 2 to 3 days and did not return to normal for 5 or more days after the dives. When a second dive followed within 3 days of the first diving episode, a decrease in fragility occurred similar to that observed 1h after the first dive. The upward trend of the fragility curve resumed within 1 day following the second dive with the increased fragility persisting for the ensuing week. Correlations of erythrocyte fragility with other biochemical components measured in the sera of these subjects are discussed. Fragility changes correlate negatively with the serum protein concentration. Positive correlations of fragility with the 3 serum enzymes measured indicate potential erythrocyte damage from the same stresses associated with diving that cause leakage of tissue enzymes into the serum. |
| Descriptors (primary) |
hyperbaric pressure; erythrocytes; diving; fragility of blood cells |
| Descriptors (secondary) |
pressure chamber tests; USA; exposure evaluation; work in pressurized atmosphere; report |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Construction industry
|
| Broad subject area(s) |
|
| Browse category(ies) |
Hyperbaric pressure
Blood diseases
|
