ILO Home
Go to the home page
Site map | Contact us Français | Espańol

CISDOC database

Document ID (ISN)26002
CIS number 76-1891
ISSN - Serial title 0013-2268 - Egészségtudomány
Year 1976
Convention or series no.
Author(s) Ruzicska P., Péter S., Laczi J., Czeizel E.
Title Study on chromosomal mutagenicity of Fundazol 50 WP
Original title A Fundazol 50 WP kromoszóma mutagenitásának vizsgálata [in Hungarian]
Bibliographic information 1976, Vol.20, No.1, p.74-83. Illus. 21 ref.
Abstract The mutagenic effects of Fundazol 50 WP (methyl 1-butylcarbamoyl-2-benzimidazolecarbamate) were studied in vivo and in vitro. The peripheral blood of workers producing the fungicide was analysed to determine exposure; there was no mutagenesis. While there was no effect on mature rats, doses of 200 and 500mg/kg/day had considerable mutagenic effects on foetal rat tissue.
Descriptors (primary) mutagenic effects; chemical industry; fungicides; benomyl; carbamates
Descriptors (secondary) toxicity evaluation; human experiments; animal experiments
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Agricultural chemicals
Chemical industry
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Amides