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Document ID (ISN)25580
CIS number 76-1359
ISSN - Serial title Cahiers de médecine du travail - Cahiers voor arbeidsgeneeskunde
Year 1976
Convention or series no.
Author(s) Susanne C., Kirsch-Volders M., Verschaeve L., Driesen M., Alexander A., Tiboldi T., Hens L.
Title Mutagenic factors in occupational medicine
Original title Mutagene factoren in de arbeidsgeneeskunde [in Dutch]
Bibliographic information June 1976, Vol.13, No.2, p.67-126. Illus. 225 ref.
Abstract Series of 7 articles on mutagenic factors encountered in workplaces. 1) Mutagenic effects on man: methods for detecting genetic effects (Susanne C.) (the best method for analysing mutagenic effects appears to be the study of human lymphocytes in vitro, or in vivo in exposed subjects). 2) Chromosome aberrations in the peripheric blood as a measurement of the mutation rate (Kirsch-Volders M.). 3) Genetic effects of lead, mercury and cadmium (Verschaeve L., Driesen M.). 4) Influence of medroxyprogesterone acetate on the karyotype (Kirsch-Volders M., Alexander A., Tiboldi T.). 5) Genetic effects of ionising radiations (Hens L.) (brief review of essential facts concerning chromosome and genome mutations in man and animmals). 6) Protection of the foetus: genetic risks involved in using ultrasound and X-rays during pregnancy (Kirsch-Volders M.) (comparative study of irradiated foetus in utero). 7) Conclusion (Susanne C.) (urgency of the problem on account of the high percentage (around 12% at birth) of congenital malformations of genetic origin).
Descriptors (primary) mutagenic effects; chromosome changes; genetic effects
Descriptors (secondary) ionizing radiation; medroxyprogesterone acetate; lymphocytes; mercury; ultrasound; x-rays; hazard evaluation; teratogenic effects; cytological effects; blood cytology; cadmium; lead
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Genetic factors in reaction to exposures
Antifertility and prenatal effects