ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)25133
CIS number 76-995
ISSN - Serial title Lavoro umano
Year 1975
Convention or series no.
Author(s) Fontana L., Siccardi M., Ardoino V.
Title Chromosome changes caused by ionising radiation.
Original title Alterazioni cromosomiche indotte da radiazioni ionizzanti. Contributo casistico [in Italian]
Bibliographic information Nov. 1975, Vol.27, No.6, p.188-200. Illus. 94 ref.
Abstract Report on observations in 4 workers who underwent moderate acute exposure to 60Co when using γ-ray testing equipment. The doses absorbed were 1.5, 9, 23rem, and an unknown quantity, respectively. Cytogenic examination of lymphocytes from the peripheral blood showed unstable chromosome changes in 3-8% of cells (the lower figure referring to the 1.5-rem exposure), and in up to 5% after one month. All other clinical examinations and tests yielded normal results. Thus the circulating lymphocytes can provide useful information on the degree of exposure. Possible modes of formation of the changes observed are discussed with reference to the literature.
Descriptors (primary) ionizing radiation; radiographic testing; chromosome changes
Descriptors (secondary) lymphocytes; case study; exposure evaluation; peripheral circulation; gamma radiation
Document type -
Subject(s) Radiation
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Ionizing radiation
Genetic factors in reaction to exposures