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Document ID (ISN)24725
CIS number 76-454
Year 1975
Convention or series no.
Author(s) Guy Y.A.
Title Examination of cutaneous tolerance to strong and weak acids and bases at various pH values
Original title Essai de tolérance cutanée à l'action d'acides et de bases fortes et faibles à des pH variables. [in French]
Bibliographic information Université de Paris VII, Faculté de médecine Xavier-Bichat, Paris, France, 1975. 33p. Illus. 23 ref.
Abstract M.D. thesis. The results are reported of cutaneous tolerance tests on guinea pigs, in order to study, among irritants, those that are corrosive to skin on account of their acidity or basicity. The experiments with histological tests were made with sulfuric, hydrochloric, nitric and acetic acids and with sodium, potassium and ammonium hydroxides. The results do not confirm the hypothesis that acids of low pH are not harmful to the skin. For bases, below pH9, the harmlessness is confirmed. All cutaneous lesions due to industrial products whose pH is equal to or less than 4, or equal to or greater than 12 should be considered as compensatable as occupational injuries.
Descriptors (primary) bases, alkalis; acids; dermatological effects; skin diseases; caustic substances
Descriptors (secondary) hydrochloric acid; sodium hydroxide; irritants; France; nitric acid; potassium hydroxide; ammonium hydroxide; thesis; animal experiments; histopathology; sulfuric acid; acetic acid
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Skin diseases
Alkaline materials
Inorganic acids
Inorganic substances