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CISDOC database

Document ID (ISN)24510
CIS number 76-415
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1975
Convention or series no.
Author(s) Gething J.
Title Tetramethyllead absorption: a report of human exposure to a high level of tetramethyllead.
Bibliographic information Nov. 1975, Vol.32, No.4, p.329-333. Illus. 15 ref.
Abstract Description of the accidental exposure of a chemical worker to a high concentration of tetramethyllead (TML) following the ejection of an autoclave valve. The worker was knocked unconscious to the floor and was covered with a mixture containing 30% TML. The resulting atmospheric lead contamination in the building was 95.7mg/m3 on the 1st floor and 376.5mg/m3 on the 2nd floor. The patient's biochemical findings are presented, discussed and compared with those of similar accidental exposures to tetraethyllead (TEL). The patient had high levels of urinary lead but no symptoms of lead poisoning; ALA levels were not significantly raised. The case described confirms that TML is less toxic to humans than TEL.
Descriptors (primary) toxic effects; petroleum refining; tetramethyllead; antiknock agents
Descriptors (secondary) case study; urinary excretion; chelation therapy; short-term exposure; urinary ala monitoring
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Petrochemical industry
Petroleum and natural gas industry