ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)24446
CIS number 76-197
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1975
Convention or series no.
Author(s) Antonjuk O.K.
Title Toxicology of complex esters of phthalic acid (literature survey)
Original title Toksikologija složnyh ėfirov ftalevoj kisloty (Obzor literatury) [in Russian]
Bibliographic information Jan. 1975, No.1, p.32-35. 38 ref.
Abstract Literature survey of the toxic effects of the following phthalates used as plasticisers in the plastics industry: dimethyl phthalate, diethyl phthalate, dibutyl phthalate, bis(2-ethylhexyl) phthalate, diisooctyl phthalate, butyl benzyl phthalate, dicapryl phthalate, didodecyl phthalate and DAP (a mixture of C7-9 and C9-11 alcohols). These phthalates are considered as only slightly toxic after one-time exposure. Their general toxicity affects nutrition absorption: slowing down of gain in body weight, impairment of hepatic and renal functions, effects on the nervous system, morphological alterations of the blood, etc. Some phthalates have allergenic and sensitising properties and cause local irritation.
Descriptors (primary) phthalates; plasticizers; toxicology
Descriptors (secondary) literature survey; dimethyl phthalate; plastics industry; dibutyl phthalate; animal experiments; diethyl phthalate
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Toxicology
Esters and salts