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CISDOC database

Document ID (ISN)24070
CIS number 75-1948
Year 1973
Convention or series no.
Author(s) Wyman Dorough H.
Title Metabolism of carbamate insecticides.
Bibliographic information Environmental Protection Agency, Research Triangle Park, North Carolina. PB-231 596/8WJ, National Technical Information Service, Springfield, Virginia 22151, USA, Sep. 1973. 255p. 85 ref. Price: Photocopy US-$6.50/Microfiche US-$1.45.
Abstract The metabolic fate of aldicarb, carbaryl and carbofuran was investigated in biological systems, and the effects of other insecticides and monoamine oxidase inhibitors on carbaryl metabolism studied in rats. Metabolic determinations were also made of 3-hydroxycarbofuran, its glucoside and glucuronide, and naphthyl glucoside. In vitro methods were developed to study mechanisms of glycosylation in insects and mammals, using 1-naphthol as model. It is recommended that development of carbamate insecticides as commercial pest control agents be encouraged; as a group, they have exhibited (1) effective insect control; (2) relatively short residual life in the environment; (3) rapid excretion from the body; and (4) polar terminal residues formed by metabolic detoxication processes.
Descriptors (primary) metabolic process; toxicology; insecticides; carbamates
Descriptors (secondary) metabolic detoxication; carbofuran; carbaryl; in vitro experiments; aldicarb; animal experiments
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Amides
Agricultural chemicals