Document ID (ISN) | 23654 |
CIS number |
75-1693 |
ISSN - Serial title |
0021-5082 - Japanese Journal of Hygiene - Nihon Eiseigaku Zasshi |
Year |
1974 |
Convention or series no. |
|
Author(s) |
Fukushima M., Sakamoto M., Kobayashi E. |
Title |
Urinary amino acid excretion in "Itai-itai" patients and inhabitants of cadmium polluted areas |
Original title |
Kadomium osenti jumin no nyochyu-yuri-aminosan haisetsu ni tuite [in Japanese] |
Bibliographic information |
Dec. 1974, Vol.29, No.5, p.498-504. Illus. 29 ref. (12 English). |
Abstract |
Aminoaciduria was widespread among patients with Itai-itai disease (chronic cadmium poisoning) living in the Jinzu River Basin area polluted with cadmium and also in inhabitants with tubular proteinuria and glucosuria in the Ichi River Basin area, where cadmium pollution has also been observed. The amino acid patterns were similar in these cases and also resembled that reported in the Fanconi syndrome. The increase in amino acid excretion in these cases seems to be due to multiple disorders of the amino acid transport systems in the renal tubules, although increased hydroxyproline excretion is ascribed to a disturbance of amino acid metabolism. |
Descriptors (primary) |
aminoaciduria; cadmium; urine monitoring; atmospheric pollution |
Descriptors (secondary) |
Japan; amino acids; survey; metabolic disturbances; urinary excretion |
Document type |
- |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
|
Browse category(ies) |
Inorganic substances Cadmium and compounds Environmental pollution Biological monitoring Air pollution Diseases of the kidney and the urinary system
|