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Document ID (ISN)23629
CIS number 75-1617
ISSN - Serial title 0959-8146 - British Medical Journal
Year 1974
Convention or series no.
Author(s) Smith L.L., Wright A., Wyatt I., Rose M.S.
Title Effective treatment for paraquat poisoning in rats and its relevance to treatment of paraquat poisoning in man.
Bibliographic information 7 Dec. 1974, p.569-571. Illus. 9 ref.
Abstract The relationships between gastrointestinal paraquat content and plasma and lung concentrations after oral administration of paraquat were studied in rats. On the basis of the findings a treatment was devised to prevent absorption of paraquat from the gut into the plasma and its accumulation in the lung. It consists of a stomach wash followed by 4 administrations of bentonite and purgatives. The relevance of this treatment to paraquat poisoning in man is discussed in view of the finding that slices of human lung accumulate paraquat in the same way as those of rat lung.
Descriptors (primary) herbicides; emergency treatment; paraquat; acute poisoning
Descriptors (secondary) paraquat chloride; ingestion; body retention; animal experiments; stomach wash-out
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Heterocyclic compounds
Agricultural chemicals