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CISDOC database

Document ID (ISN)23603
CIS number 75-1613
ISSN - Serial title 0019-8366 - Industrial Health
Year 1974
Convention or series no.
Author(s) Koizumi A., Dobashi Y., Tachibana Y., Tsuda K., Katsunuma H.
Title Cytokinetic and cytogenetic changes in cultured human leucocytes and HeLa cells induced by benzene.
Bibliographic information June 1974, Vol.12, No.1-2, p.23-29. Illus. 17 ref.
Abstract The methods for chromosome analysis and determination of DNA synthesis and the results of this experimental study with human whole blood are described. The findings concerning decreased DNA synthesis in leucocytes and HeLa cells, and chromosomal gaps and breaks, are discussed in relation to the findings of other authors.
Descriptors (primary) benzene; chromosome changes; leukocyte anomalies
Descriptors (secondary) DNA; description of technique; analysis of chromosome aberrations
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Aromatic hydrocarbons
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Blood diseases