| Document ID (ISN) | 23435 |
| CIS number |
75-1368 |
| ISSN - Serial title |
0009-9309 - Clinical Toxicology |
| Year |
1974 |
| Convention or series no. |
|
| Author(s) |
Wills J.H., Coulston F., Harris E.S., McChesney E.W., Russell J.C., Serrone D.M. |
| Title |
Inhalation of aerosolized ethylene glycol by man. |
| Bibliographic information |
Oct. 1974, Vol.7, No.5, p.463-476. Illus. 27 ref. |
| Abstract |
After a brief review of the literature and a description of the signs and symptoms observed after experimental ethylene glycol ingestion, the authors present their own experiments in humans, in which 19 male volunteers were exposed to aerosolized ethylene glycol in mean daily concentrations of 3-67mg/m3 almost continually for 4 weeks. Blood and urine examinations gave no evidence of the absorption of important quantities of ethylene glycol. There were no serious signs of toxicity but some complaints of irritation of the upper respiratory tract. Irritation became common with an ethylene glycol concentration of 140mg/m3, and more than 200mg/m3 was intolerable. It was concluded that an individual with normal sensory apparatus could not absorb a harmful quantity of ethylene glycol through the respiratory tract. Detailed results of laboratory and psychometric tests are given in tables. |
| Descriptors (primary) |
ethylene glycol; inhalation toxicity; toxicology |
| Descriptors (secondary) |
irritation; human experiments; aerosols |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Glycols
Alcohols
|
