Document ID (ISN) | 23144 |
CIS number |
75-1045 |
ISSN - Serial title |
Cahiers de notes documentaires - Sécurité et hygiène du travail |
Year |
1974 |
Convention or series no. |
|
Author(s) |
Guillerm R., Hee J., Bourdin M., Burnet H., Siou G. |
Title |
Contribution to determination of the threshold limit concentration of acrolein |
Original title |
Contribution à la détermination de la valeur limite de concentration de l'acroléine. [in French] |
Bibliographic information |
4th quarter 1974, No.77, Note No.926-77-74, p.527-535. Illus. 19 ref. |
Abstract |
The authors studied the chronic effects of exposure to acrolein in concentrations of 1 and 2ppm in rats. Material and methods used for the experiments, results of examinations (weight curves, pulmonary resistance, haematological findings, vanylmandelic acid levels, pulmonary surfactant, histopathology). The most notable result is the fact that most of the parameters studied showed no correlation between the effect (retardation of growth, histological changes of the lower respiratory tract) and the duration of exposure. |
Descriptors (primary) |
toxicology; acrolein; chronic toxicity |
Descriptors (secondary) |
animal experiments; pulmonary surfactant assessment; determination of exposure limits |
Document type |
- |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Aldehydes
|