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Document ID (ISN)23144
CIS number 75-1045
ISSN - Serial title Cahiers de notes documentaires - Sécurité et hygiène du travail
Year 1974
Convention or series no.
Author(s) Guillerm R., Hee J., Bourdin M., Burnet H., Siou G.
Title Contribution to determination of the threshold limit concentration of acrolein
Original title Contribution à la détermination de la valeur limite de concentration de l'acroléine. [in French]
Bibliographic information 4th quarter 1974, No.77, Note No.926-77-74, p.527-535. Illus. 19 ref.
Abstract The authors studied the chronic effects of exposure to acrolein in concentrations of 1 and 2ppm in rats. Material and methods used for the experiments, results of examinations (weight curves, pulmonary resistance, haematological findings, vanylmandelic acid levels, pulmonary surfactant, histopathology). The most notable result is the fact that most of the parameters studied showed no correlation between the effect (retardation of growth, histological changes of the lower respiratory tract) and the duration of exposure.
Descriptors (primary) toxicology; acrolein; chronic toxicity
Descriptors (secondary) animal experiments; pulmonary surfactant assessment; determination of exposure limits
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Aldehydes