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Document ID (ISN)23134
CIS number 75-1103
ISSN - Serial title 0387-2289 - St. Marianna Medical Journal
Year 1975
Convention or series no.
Author(s) Tane S., Muromoto M., Eiko K., Ushigome S.
Title Ocular injury by paraquat (herbicide) - Report of a case
Original title Kyoroyoku-setsushyoku-gata joso-zai Paraquat no tobiiri ni yoru me-shyogai no chiryo-rei [in Japanese]
Bibliographic information Sep. 1974, Vol.2, No.3, p.274-278. Illus. 9 ref.
Abstract Report of a case of eye injury in a 66-year-old man due to accidental splashing of a herbicide solution containing 24% paraquat. The lesions produced were chemosis, corneal erosion and extensive formation of a conjunctival pseudomembrane. These corneal and conjunctival lesions persisted for about 16 weeks. Since the solution was almost neutral (pH 6.7), the mechanism of this harmful effect is somewhat unclear. Histological examination showed the conjunctiva to be composed of a totally eroded and partly ulcerated epithelial layer and subepithelial tissue with marked oedema and inflammatory cell reaction predominantly of lymphocytes and plasma cells. Foci of dense lymphoid infiltration were prominent. The surface was covered by a thick fibrin and inflammatory exudate. Blood capillaries were proliferated and dilated. The inflammation appeared to be of toxic and/or possibly of allergic origin.
Descriptors (primary) herbicides; eye injuries; paraquat
Descriptors (secondary) case study; conjunctivitis; corneal damage; paraquat chloride
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Heterocyclic compounds
Agricultural chemicals