Document ID (ISN) | 23134 |
CIS number |
75-1103 |
ISSN - Serial title |
0387-2289 - St. Marianna Medical Journal |
Year |
1975 |
Convention or series no. |
|
Author(s) |
Tane S., Muromoto M., Eiko K., Ushigome S. |
Title |
Ocular injury by paraquat (herbicide) - Report of a case |
Original title |
Kyoroyoku-setsushyoku-gata joso-zai Paraquat no tobiiri ni yoru me-shyogai no chiryo-rei [in Japanese] |
Bibliographic information |
Sep. 1974, Vol.2, No.3, p.274-278. Illus. 9 ref. |
Abstract |
Report of a case of eye injury in a 66-year-old man due to accidental splashing of a herbicide solution containing 24% paraquat. The lesions produced were chemosis, corneal erosion and extensive formation of a conjunctival pseudomembrane. These corneal and conjunctival lesions persisted for about 16 weeks. Since the solution was almost neutral (pH 6.7), the mechanism of this harmful effect is somewhat unclear. Histological examination showed the conjunctiva to be composed of a totally eroded and partly ulcerated epithelial layer and subepithelial tissue with marked oedema and inflammatory cell reaction predominantly of lymphocytes and plasma cells. Foci of dense lymphoid infiltration were prominent. The surface was covered by a thick fibrin and inflammatory exudate. Blood capillaries were proliferated and dilated. The inflammation appeared to be of toxic and/or possibly of allergic origin. |
Descriptors (primary) |
herbicides; eye injuries; paraquat |
Descriptors (secondary) |
case study; conjunctivitis; corneal damage; paraquat chloride |
Document type |
- |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
|
Browse category(ies) |
Heterocyclic compounds Agricultural chemicals
|