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Document ID (ISN)22725
CIS number 75-802
ISSN - Serial title 0009-0573 - Československá hygiena
Year 1974
Convention or series no.
Author(s) Líška D., Tildyová K.
Title Study of the changes of the activity of certain enzymes in the blood of pilots and mechanics exposed to organophosphorus pesticides
Original title Štúdium zmien aktivity niektorých enzýmov v krvi pilotov a mechanikov, exponovaných organofosforovým pesticídom [in Slovak]
Bibliographic information July 1974, Vol.19, No.6-7, p.289-295. Illus. 15 ref.
Abstract The authors examined the changes in cholinesterase activity, and blood levels of glutamic-oxalacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), alkaline phosphatase, lactic dehydrogenase (LDH) and their isoenzymes in pilots and mechanics engaged in crop-dusting operations with organophosphorus pesticides. Exposure to these pesticides resulted in erythrocyte and plasma cholinesterase inhibition and increased GPT and LDH isoenzyme activity (particularly that of LDH5). The effect of exposure on GOT and alkaline phosphatase was not confirmed. Occupational exposure had lasted for 3 to 19 years (average 7.6 years). These results show the urgent need for preventive measures in this field.
Descriptors (primary) organophosphorus compounds; enzyme disturbances; agriculture; crop protection; pesticides
Descriptors (secondary) lactate dehydrogenase; alkaline phosphatases; cholinesterase; long-term exposure; glutamic-oxalacetic transaminase; aircraft; glutamic-pyruvic transaminase
Document type -
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Agricultural chemicals
Blood diseases