| Document ID (ISN) | 22725 |
| CIS number |
75-802 |
| ISSN - Serial title |
0009-0573 - Československá hygiena |
| Year |
1974 |
| Convention or series no. |
|
| Author(s) |
Líška D., Tildyová K. |
| Title |
Study of the changes of the activity of certain enzymes in the blood of pilots and mechanics exposed to organophosphorus pesticides |
| Original title |
Štúdium zmien aktivity niektorých enzýmov v krvi pilotov a mechanikov, exponovaných organofosforovým pesticídom [in Slovak] |
| Bibliographic information |
July 1974, Vol.19, No.6-7, p.289-295. Illus. 15 ref. |
| Abstract |
The authors examined the changes in cholinesterase activity, and blood levels of glutamic-oxalacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), alkaline phosphatase, lactic dehydrogenase (LDH) and their isoenzymes in pilots and mechanics engaged in crop-dusting operations with organophosphorus pesticides. Exposure to these pesticides resulted in erythrocyte and plasma cholinesterase inhibition and increased GPT and LDH isoenzyme activity (particularly that of LDH5). The effect of exposure on GOT and alkaline phosphatase was not confirmed. Occupational exposure had lasted for 3 to 19 years (average 7.6 years). These results show the urgent need for preventive measures in this field. |
| Descriptors (primary) |
organophosphorus compounds; enzyme disturbances; agriculture; crop protection; pesticides |
| Descriptors (secondary) |
lactate dehydrogenase; alkaline phosphatases; cholinesterase; long-term exposure; glutamic-oxalacetic transaminase; aircraft; glutamic-pyruvic transaminase |
| Document type |
- |
| Subject(s) |
Agriculture, fishing, animal husbandry
|
| Broad subject area(s) |
|
| Browse category(ies) |
Agricultural chemicals
Blood diseases
Agriculture
|
