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Document ID (ISN)22598
CIS number 75-484
ISSN - Serial title 0098-7484 - Journal of the American Medical Association
Year 1974
Convention or series no.
Author(s) Taylor J.S., Shmunes E., Holmes A.W.
Title Hepatitis B in plasma fractionation workers.
Bibliographic information 11 Nov. 1974, Vol.230, No.6, p.850-853. 18 ref.
Abstract Between 1968 and 1971, hepatitis B occurred at a plasma fractionation company in 14 employees who had worked for 18 months or less (9.4% of the workers at risk). Plasma dumping, a manual operation involving handling of incoming plasma (resulting in frequent minor cuts on glass bottles or sharp instruments), a task to which new employees tend to be assigned, appears to entail the greatest risk. Other procedures considered hazardous are manual scraping of fibrinogen from centrifuges, and processing and aerosolisation of plasma fractions (splashing on mucous membranes of face). The degree of contact correlated directly with the prevalence of antibody in the population studied. Prophylactic recommendations cover general hygiene and safety measures. Periodic monitoring of exposed employees is strongly recommended.
Descriptors (primary) blood plasma; pharmaceutical industry; infectious hepatitis
Descriptors (secondary) viruses; epidemiologic study; serological reactions; skin microtrauma; enzyme activity determination
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Liver diseases
Pharmaceutical industry
Bacterial and parasitic diseases
Viral diseases (other than aids)