|
|
 |
|
|
CISDOC database
| Document ID (ISN) | 22590 |
| CIS number |
75-455 |
| ISSN - Serial title |
0041-008X - Toxicology and Applied Pharmacology |
| Year |
1974 |
| Convention or series no. |
|
| Author(s) |
Torkelson T.R., Leong B.K.J., Kociba R.J., Richter W.A., Gehring P.J. |
| Title |
1,4-Dioxane - II. Results of a 2-year inhalation study in rats. |
| Bibliographic information |
Nov. 1974, Vol.30, No.2, p.287-298. Illus. 12 ref. |
| Abstract |
Rats were exposed to an average concentration of 0.4mg/l of 1,4-dioxane vapours 7h/day, 5days/week for 2 years. Neither histopathological changes nor tumours resulted. There was no adverse effects on demeanour, growth, mortality, haematological findings, biochemical determinations or body weight. At the time of this study, the TLV for dioxane was set at 0.36mg/l (100ppm). |
| Descriptors (primary) |
dioxane; inhalation; toxicology |
| Descriptors (secondary) |
threshold limit values; long-term study; animal experiments |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Ethers
|
|
|
|
|
|
