| Document ID (ISN) | 22578 |
| CIS number |
75-448 |
| ISSN - Serial title |
0013-9351 - Environmental Research |
| Year |
1974 |
| Convention or series no. |
|
| Author(s) |
Miller A.T., Woods J.J. |
| Title |
Effects of acute carbon monoxide exposure on the energy metabolism of rat brain and liver. |
| Bibliographic information |
Aug. 1974, Vol.8, No.1, p.107-111. Illus. 5 ref. |
| Abstract |
Exposure of rats to carbon monoxide (500 or 1,000ppm in air for 2.5h) reduced the surface oxygen tension of liver to zero but brain oxygen tension only by one-half. Metabolic changes were similarly much greater in liver than in brain but were less in both organs than might have been expected from the magnitude of the surface oxygen tension changes. The validity of assessing oxygen availability from surface oxygen tension measurements is questioned. |
| Descriptors (primary) |
liver; brain; energy metabolism; carbon monoxide |
| Descriptors (secondary) |
metabolic process; enzyme activity determination; animal experiments; carboxyhaemoglobin level |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Carbon monoxide
Inorganic substances
|
