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CISDOC database

Document ID (ISN)22534
CIS number 75-435
ISSN - Serial title 0041-008X - Toxicology and Applied Pharmacology
Year 1974
Convention or series no.
Author(s) Klaassen C.D.
Title Biliary excretion of arsenic in rats, rabbits, and dogs.
Bibliographic information Sep. 1974, Vol.29, No.3, p.447-457. Illus. 10 ref.
Abstract Studies were carried out in rats, dogs and rabbits to determine if arsenic is transported from the plasma to the bile against a concentration gradient and if biliary excretion is important in the removal of arsenic from the body. It was shown that arsenic is excreted into the bile against a large bile/plasma concentration gradient in rats, suggesting excretion by an active transport mechanism.
Descriptors (primary) arsenic; biliary excretion; toxicology
Descriptors (secondary) detection by radioactivity; animal experiments; metabolic process
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Arsenic and compounds
Inorganic substances