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CISDOC database

Document ID (ISN)22469
CIS number 75-419
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1974
Convention or series no.
Author(s) Legator M.S.
Title Mutagenesis and its environmental implications.
Bibliographic information Oct. 1974, Vol.16, No.10, p.672-675. 9 ref.
Abstract Continuing and expanded efforts in evaluating chemicals for mutagenicity are urgently needed since many chemicals to which humans are exposed have not been tested in this regard. This article deals with: (a) the prevalence of genetic syndromes in the population; (b) the difficulties of detecting specific mutagenic chemicals in humans; and (c) the practical animal procedures at present available for characterising mutagenic compounds. Routine screening of chemicals in the environment and testing of new materials before their marketing offer the most practical means of eliminating agents that contribute to the high incidence of genetic abnormalities.
Descriptors (primary) mutagens; hazard evaluation; toxicology; chemical industry
Descriptors (secondary) exposure evaluation; animal experiments; medical supervision; genetic effects; in vitro experiments
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Risk evaluation
Chemical industry
Genetic factors in reaction to exposures