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CISDOC database

Document ID (ISN)22445
CIS number 75-413
ISSN - Serial title Work - Environment - Health
Year 1974
Convention or series no.
Author(s) Axelson O., Sundell L.
Title Herbicide exposure, mortality and tumor incidence. An epidemiological investigation on Swedish railroad workers.
Bibliographic information 1974, Vol.11, No.1, p.21-28. Illus. 15 ref.
Abstract An epidemiological investigation of tumour incidence and mortality among Swedish railroad workers exposed to different herbicides showed a significantly increased tumour incidence and mortality among workers exposed to amitrol (3-amino-1,2,4-triazole), and a normal tumour incidence and mortality among those exposed to phenoxy acids (2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid). Exposure to amitrol was sometimes associated with exposure to 3-(3,4-dichlorophenyl)-1,1-dimethylurea (diuron) and 3-(p-chlorophenyl)-1,1-dimethylurea (monuron), which confuses the evaluation of the relationship between amitrol exposure and tumour incidence. Nevertheless, as the results are in agreement with those based on animal experiments, caution in using amitrol is advocated.
Descriptors (primary) herbicides; mortality; neoplasms; rail transport; track operations
Descriptors (secondary) Sweden; dichlorophenoxyacetic acid; epidemiologic study; aminotriazole; hazard evaluation; trichlorophenoxyacetic acid
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Rail transportation
Agricultural chemicals