| Document ID (ISN) | 22332 |
| CIS number |
75-163 |
| ISSN - Serial title |
Archiv für Toxikologie |
| Year |
1973 |
| Convention or series no. |
|
| Author(s) |
Khan H., Khan M.H. |
| Title |
Cytogenetic studies following chronic exposure to benzene |
| Original title |
Cytogenetische Untersuchungen bei chronischer Benzolexposition [in German] |
| Bibliographic information |
1973, Vol.31, No.1, p.39-49. Illus. 40 ref. |
| Abstract |
Results of examinations carried out on 15 workers exposed to benzene for periods of 2 to 20 years and on 14 healthy controls (leucocyte culture and direct analysis of bone marrow). A higher percentage of stable and unstable chromosome aberrations was observed among the exposed workers than among the controls. Variations in length of exposure seemed to play only a minor role. In one case myelopathy due to benzene was observed. The authors conclude that cytogenetic examinations are a useful diagnostic method for assessing the degree of benzene poisoning. |
| Descriptors (primary) |
benzene; benzene myelopathy; cytogenetic studies; cytotoxic effects; chromosome changes |
| Descriptors (secondary) |
diagnosis; comparative study; analysis of chromosome aberrations; long-term exposure |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Aromatic hydrocarbons
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Blood diseases
|
