ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)22307
CIS number 75-195
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1974
Convention or series no.
Author(s) Efimenko L.P.
Title Data on the evaluation of the gonadotropic and mutagenic effects of the herbicide mixture butyl ether/2,4,5-T
Original title (Materialy k ocenke gonadotropnogo i mutagennogo dejstvija gerbicida butylovogo ėfira 2,4,5-T [in Russian]
Bibliographic information Apr. 1974, No.4, p.24-27. 12 ref.
Abstract Description and results of animal experiments designed to determine the systemic toxicity and the gonadotropic and mutagenic effects of the herbicide mixture butyl ether and 2,4,5-trichlorophenoxyacetic acid. The author establisehd a close correlation between the cytogenic effect and the dose; he situated the threshold dose in the region of 0.01mg/kg and the threshold of systemic toxicity in chronic exposure conditions at around 0.1mg/kg; the last-mentioned dose is also the threshold for the gonadotropic effect.
Descriptors (primary) mutagenic effects; herbicides; gonadotropic effects; trichlorophenoxyacetic acid; toxicology; dibutyl ether
Descriptors (secondary) animal experiments; dose-response relationship; biological threshold limits
Document type -
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Agricultural chemicals
Genetic factors in reaction to exposures
Antifertility and prenatal effects