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CISDOC database

Document ID (ISN)22276
CIS number 75-194
ISSN - Serial title 0020-5923 - Internationales Archiv für Arbeitsmedizin - International Archives of Occupational Health
Year 1974
Convention or series no.
Author(s) Dési I.
Title Neurotoxicological effect of small quantities of lindane - Animal studies.
Bibliographic information 10 July 1974, Vol.33, No.2, p.153-162. Illus. 17 ref.
Abstract The early effects of low doses of lindane (2.5 to 50 mg/kg) on the functions of the central nervous system were studied in rats by means of learning tests. The results showed that these functional tests are suitable for the early detection of slight impairments of the nervous system, whereas liver function tests and histological examinations performed at the same time were negative. Therefore, physiological examination of persons exposed to lindane is recommended as a preventive measure. The neuurotoxicological methods may detect minimal pesticide contamination in the reversible phase when other less sensitive tests are negative.
Descriptors (primary) neurotoxic effects; exposure evaluation; pesticides; lindane
Descriptors (secondary) learning performance tests; animal experiments
Document type -
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Agricultural chemicals
Exposure evaluation
Diseases of the nervous system
Halogenated hydrocarbons