ILO Home
Go to the home page
Site map | Contact us Français | Espańol

CISDOC database

Document ID (ISN)21698
CIS number 74-1714
ISSN - Serial title 0041-008X - Toxicology and Applied Pharmacology
Year 1974
Convention or series no.
Author(s) Dési I., Gönczi L., Simon G., Farkas I., Kneffel Z.
Title Neurotoxicologic studies of two carbamate pesticides in subacute animal experiments.
Bibliographic information Mar. 1974, Vol.27, No.3, p.465-476. Illus. 19 ref.
Abstract 2 pesticides, carbaryl (1-naphthyl methylcarbamate) and arprocarb (2-isopropoxyphenyl methylcarbamate) were tested for neurotoxic effects in subacute experiments on rats. The authors examined the process of learning and performance of a previously learned task, and studied EEG patterns under resting conditions and under rhythmic light stimulation. The cholinesterase activity of the blood and of various parts of the brain was recorded. The findings in these animal experiments suggest that the early signs of possible subacute intoxication may be measured in humans by EEG and objective tests of psychological performance.
Descriptors (primary) neurotoxic effects; arprocarb; carbaryl; toxicology; pesticides
Descriptors (secondary) cholinesterase; electroencephalography; enzyme activity determination; learning performance tests; animal experiments
Document type -
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Agricultural chemicals
Diseases of the nervous system