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Document ID (ISN)21494
CIS number 74-1394
Year 1973
Convention or series no.
Author(s) Neige G.
Title Hepatic cellular lesions in the course of experimental poisoning by a cadmium salt
Original title Lésions cellulaires hépatiques au cours d'une intoxication expérimentale par un sel cadmique. [in French]
Bibliographic information Université de Paris V, Faculté de médecine Cochin - Port-Royal, Paris, France, 1973. 61p. Illus. 116 ref.
Abstract MD thesis. Part 1: industrial uses of cadmium, clinical and biological symptoms, physiopathology. Part 2: literature survey of liver damage in human pathology and animal experiments. Part 3: animal experiments; here, by using optical and electron microscopy, the exact nature and extent of hepatic cell impairment due to poisoning of short duration can be ascertained. Nothing was observed by optical microscopy, whereas tissue examination by electron microscopy disclosed, on the 60th day, the presence of numerous intranuclear inclusions, of leafy aspect, which would lead one to suspect lipid changes, as well as large zones of cytoplasmic necrosis.
Descriptors (primary) cadmium and compounds; histopathology; toxicology; hepatotoxic effects
Descriptors (secondary) literature survey; France; symptoms; excretion; body retention; animal experiments; electron microscopy; cadmium; uses; thesis
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Cadmium and compounds
Inorganic substances