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Document ID (ISN)21441
CIS number 74-1422
ISSN - Serial title 0004-1254 - Arhiv za higijenu rada i toksikologiju
Year 1973
Convention or series no.
Author(s) Kolmodin-Hedman B.
Title Changes in drug metabolism and lipoproteins in workers occupationally exposed to DDT and lindane.
Bibliographic information 1973, Vol.24, No.4, p.289-296. Illus. 15 ref.
Abstract Communication to the Swedish-Yugoslav symposium on pesticides (Milocer, Yugoslavia, 4-8 Dec. 1972). In 26 men occupationally exposed mainly to lindane and DDT, antipyrine had a significantly shorter plasma half-life than in 33 control subjects. 22 men exposed mainly to lindane and DDT and 38 unexposed healthy males were studied with regard to their fasting serum lipid levels and the amounts of lipids in the 3 ultracentrifugally separated lipoprotein families. Plasma levels of lindane, p,p'-DDE and p,p'-DDT were determined in 42 spraymen exposed to lindane and 23 nursery workers with a low and intermittent exposure to DDT. The plasma lindane levels of the exposed groups differed significantly from those of the control groups. The plasma DDE and DDT values of the exposed persons did not differ from those controls with only low dietary exposure to DDT.
Descriptors (primary) metabolic process; DDT; pesticides; drugs; lipoproteins; lindane
Descriptors (secondary) DDE; comparative study; gas chromatography; antipyrine
Document type -
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Halogenated hydrocarbons
Agricultural chemicals