| Document ID (ISN) | 21350 |
| CIS number |
74-1356 |
| ISSN - Serial title |
0025-7818 - Medicina del lavoro |
| Year |
1973 |
| Convention or series no. |
|
| Author(s) |
Saia B., Rossi A., Mastrangelo G. |
| Title |
Epidemiological survey of respiratory function alterations in exposure to isocyanates |
| Original title |
Indagine epidemiologica sulle alterazioni della funzionalità respiratoria nella esposizione a isocianati [in Italian] |
| Bibliographic information |
Mar.-Apr. 1973, Vol.64, No.3-4, p.143-150. 8 ref. |
| Abstract |
Study of 46 workers exposed to toluene diisocyanate in a refrigerator factory. In the majority of cases, spirographic changes were found, characterised by a reduction in pulmonary volume directly proportional to the total duration of exposure to the hazard, and more frequent in those working at ovens where exposure is the most severe. The isocyanate may cause both an allergic asthma and direct respiratory lesions; in some cases, both mechanisms are combined. This is confirmed by the presence of anti-toluene diisocyanate antibodies in relation to the most significant changes in respiratory function, which are often an aggravating factor. |
| Descriptors (primary) |
tolylene diisocyanate; plastics converting industry; functional respiratory disorders; expanded plastics |
| Descriptors (secondary) |
2,4-tolylene diisocyanate; allergic asthma; serological reactions; dose-response relationship; respiratory impairment; epidemiologic study |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Cyano compounds
Diseases of the respiratory system (except for pneumoconiosis & similar)
Isocyanates
|
