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Document ID (ISN)20985
CIS number 74-1036
ISSN - Serial title 0004-1254 - Arhiv za higijenu rada i toksikologiju
Year 1973
Convention or series no.
Author(s) Wilhelm K., Pleština R., Svetličić B.
Title Blood cholinesterase activity in workers exposed to the organophosphorus insecticide Ekatin
Original title Aktivnost kolinesteraza u krvi radnika izloženih organskom fosfornom insekticidu Ekatinu [in Serbocroatian]
Bibliographic information 1973, Vol.24, No.2, p.107-116. 15 ref.
Abstract To evaluate the exposure level in a pesticide formulating plant, 16 workers engaged in the production of Ekatin, a 20% solution of thiometon (S-[2-(ethylthio)ethyl]0,0-dimethyl ester), were medically supervised for 6 weeks. The acute toxicity of thiometon had been determined in preliminary animal experiments and its inhibitory action on human blood cholinesterase examined in vitro. The results, which are tabulated, were used to evaluate the hazard to which pesticide workers are exposed and to select appropriate methods for measuring blood cholinesterase activity.
Descriptors (primary) organophosphorus compounds; insecticides; enzyme disturbances
Descriptors (secondary) thiometon; exposure tests; cholinesterase
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Blood diseases
Agricultural chemicals