Document ID (ISN) | 20985 |
CIS number |
74-1036 |
ISSN - Serial title |
0004-1254 - Arhiv za higijenu rada i toksikologiju |
Year |
1973 |
Convention or series no. |
|
Author(s) |
Wilhelm K., Pleština R., Svetličić B. |
Title |
Blood cholinesterase activity in workers exposed to the organophosphorus insecticide Ekatin |
Original title |
Aktivnost kolinesteraza u krvi radnika izloženih organskom fosfornom insekticidu Ekatinu [in Serbocroatian] |
Bibliographic information |
1973, Vol.24, No.2, p.107-116. 15 ref. |
Abstract |
To evaluate the exposure level in a pesticide formulating plant, 16 workers engaged in the production of Ekatin, a 20% solution of thiometon (S-[2-(ethylthio)ethyl]0,0-dimethyl ester), were medically supervised for 6 weeks. The acute toxicity of thiometon had been determined in preliminary animal experiments and its inhibitory action on human blood cholinesterase examined in vitro. The results, which are tabulated, were used to evaluate the hazard to which pesticide workers are exposed and to select appropriate methods for measuring blood cholinesterase activity. |
Descriptors (primary) |
organophosphorus compounds; insecticides; enzyme disturbances |
Descriptors (secondary) |
thiometon; exposure tests; cholinesterase |
Document type |
- |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Blood diseases Agricultural chemicals
|