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Document ID (ISN)20899
CIS number 74-788
ISSN - Serial title 0028-0836 - Nature
Year 1974
Convention or series no.
Author(s) O'Riordan M.L., Evans H.J.
Title Absence of significant chromosome damage in males occupationally exposed to lead.
Bibliographic information 4 Jan. 1974, Vol.247, No.5435, p.50-53. 20 ref.
Abstract A study of the extent of chromosome damage in a population of men occupationally exposed to oxides of lead. 70 male workers employed by a shipbreaking yard were investigated. The results do not indicate an increased chromosome aberration frequency in the peripheral blood lymphocytes of individuals chronically exposed to high levels of lead. Difficulties which may be encountered in the interpretation of chromosome aberration data are discussed, and the conflicting results of previous studies into the possible mutagenic effects of lead are evaluated.
Descriptors (primary) gas cutting; lead; chromosome changes; shipbreaking; lead tetroxide
Descriptors (secondary) mutagenic effects; long-term exposure; survey
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Shipwrecking
Lead and compounds
Welding and cutting
Inorganic substances