ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)20860
CIS number 74-780
Year 1972
Convention or series no.
Author(s) Bojcov A.N., Rotenberg Ju.S., Mulenkova V.G.
Title Toxicological evaluation of chloral liberated during spraying and moulding of polyurethane foam
Original title Evaluation toxicologique du chloral libéré lors du pistoletage et du coulage de mousses de polyuréthane. [in French]
Bibliographic information Translation INRS 123 B-72, Institut national de recherche et de sécurité, 30 rue Olivier-Noyer, 75680 Paris Cedex 14, France, 1972. 9p. 2 ref.
Abstract French translation of: K voprosu o toksikologiceskoj ocenke hloralja v processe ego vydelenija pri napylenii i zalivke penopoliuretanov. Gigiena truda i professional'nye zabolevanija, Moskva, USSR, June 1970, Vol.14, No.6, p.26-29. 2 ref. Occupational hygiene studies carried out during the application of certain polyurethane foams used for insulation, etc. disclosed that, in addition to isocyanates, tertiary amines, etc., chloral (CCl3CHO) also was given off during spraying or moulding. Chloral readily combines with water and water vapour to form chloral hydrate which is known to be acutely toxic (LD50=710 mg/kg, LC50=32 mg/l). Study of the toxic properties of chloral hydrate in cases of chronic exposure has shown that a concentration of 0.06 mg/l is already toxic and that a concentration of 0.02 mg/l is very close to the threshold limit value. The authors recommend that the ceiling value for chloral in air be fixed at 10 mg/m3.
Descriptors (primary) threshold limit values; polyurethanes; toxicology; expanded plastics; chloral
Descriptors (secondary) chloral hydrate; translation; animal experiments
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Occupational exposure limits
Aldehydes