| Document ID (ISN) | 20834 |
| CIS number |
74-674 |
| ISSN - Serial title |
0013-9351 - Environmental Research |
| Year |
1973 |
| Convention or series no. |
|
| Author(s) |
Zaidi S.H., Dogra R.K.S., Shanker R., Chandra S.V. |
| Title |
Experimental infective manganese pneumoconiosis in guinea pigs. |
| Bibliographic information |
Sep. 1973, Vol.6, No.3, p.287-297. Illus. 30 ref. |
| Abstract |
To assess the role of an infective factor in the production of manganese pneumoconiosis, guinea pigs were intratracheally inoculated with only Candida ablicans (a facultative pathogen of the upper respiratory tract), only manganese dioxide or a combination of both. Histopathological studies revealed at the termination of the experiments (180 days) that the dust and organism together produced thick reticulin and collagen fibrosis in the lungs; manganese dioxide alone produced a fibrotic reaction comprised of only thick reticulin fibres, while the organism alone produced slight lymphoid hyperplasia and no fibrosis. |
| Descriptors (primary) |
manganese dioxide; Candida albicans; manganese pneumoconiosis; dust; infectious diseases |
| Descriptors (secondary) |
connective tissue development; histopathology; animal experiments |
| Document type |
- |
| Subject(s) |
Dust, aerosols and related diseases
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Bacterial and parasitic diseases
Pneumoconioses
|
