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Document ID (ISN)20625
CIS number 74-731
ISSN - Serial title 0032-6291 - Pracovní lékařství
Year 1973
Convention or series no.
Author(s) Macúch P., Jindra J., Aujezdská A.
Title Relation between the elimination of chlortetracycline in urine and occupational exposure to this biological stimulant
Original title Vylučování chlórtetracyklinu močí v závislosti na profesionální exposici tomuto biostimulátoru [in Czech]
Bibliographic information Apr. 1973, Vol.25, No.4, p.130-134. Illus. 17 ref.
Abstract The use of chlortetracycline (aureomycin) as a biological stimulant for the nutrition of domestic animals raises hygiene problems for persons working in environments contaminated by this substance. The authors studied experimentally the relationship between urinary excretion of chlortetracycline and degree of exposure, and then checked the results found in 13 persons working in a livestock fodder production plant. Manifest antibiotic activity was found in 54% of the urine samples. The maximum values recorded correspond to a daily level per os of 20 µg of chlortetracycline/kg of body weight; 20% of the positive results correspond to a level of 1 to 15 µg and 79% to a level lower than 1 µg.
Descriptors (primary) livestock rearing; feed production; dose-response relationship
Descriptors (secondary) chlortetracycline; urine monitoring; human experiments
Document type -
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Livestock rearing
Food industry