| Document ID (ISN) | 20484 |
| CIS number |
74-470 |
| ISSN - Serial title |
1040-8444 - Critical Reviews in Toxicology |
| Year |
1971 |
| Convention or series no. |
|
| Author(s) |
Gehring P.J. |
| Title |
The cataractogenic activity of chemical agents. |
| Bibliographic information |
Sep. 1971, Vol.1, No.1, p.93-118. Illus. 224 ref. |
| Abstract |
A comprehensive discussion of miscellaneous cataractogenic drugs and chemicals. As this subject has previously been given little attention, few toxicologists are familiar with the normal lens structure, physiology, chemistry and function. These items are reviewed in an introduction to the article. Techniques to predict the cataractogenic effects of chemicals in man are discussed, bearing in mind such complicating factors as: species differences in the response of animals to cataractogenic agents; the high incidence of spontaneous cataracts in some species and strains; some chemicals being cataractogenic only in the presence of sunlight; the possible presence of other causes of cataract. |
| Descriptors (primary) |
toxic cataract; cataractogenic effects; toxic substances |
| Descriptors (secondary) |
solar radiation; literature survey; trinitrotoluene; 2,6-dichloro-4-nitroaniline; naphthalene; diquat; 2,4-dinitrophenol; synergism; dimethyl sulfoxide |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Diseases of the eye and vision damage
|
