| Document ID (ISN) | 20142 |
| CIS number |
74-142 |
| ISSN - Serial title |
0041-008X - Toxicology and Applied Pharmacology |
| Year |
1972 |
| Convention or series no. |
|
| Author(s) |
Epstein S.S., Arnold E., Andrea J., Bass W., Bishop Y. |
| Title |
Detection of chemical mutagens by the dominant lethal assay in the mouse. |
| Bibliographic information |
Oct. 1972, Vol.23, No.2, p.288-325. Illus. 20 ref. |
| Abstract |
Data are given on 174 agents (including pharmaceuticals, industrial chemicals, carcinogens, food additives, pesticides, air and water pollutants) tested in the modified dominant lethal assay. The range in variability of various reproductive parameters is analysed in concurrent control populations. Based on these analyses, standard criteria for the evaluation of dominant lethal assay data are developed. |
| Descriptors (primary) |
toxic substances; mutagenic effects |
| Descriptors (secondary) |
pharmaceutical products; dimethyl sulfate; aflatoxin G1; formaldehyde; carcinogens; 1,1,2-trichloro-1,2,2-trifluoroethane; tert-butyl hydroperoxide; manganese chloride; benzanthrone; trimethyl phosphate; propiolactone; hydrazine; p-dimethylaminoazobenzene; aflatoxin B1; cumene hydroperoxide; cumyl peroxide; benzoyl peroxide; ethyl carbamate; dimethylnitrosoamine; methyl carbamate; 1,1-dimethylhydrazine; pesticides; epichlorohydrin; benzo(a)pyrene; diepoxybutane; food additives; animal experiments; tetrachlorodifluoroethane; acrolein; 4-nitroquinoline N-oxide |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Genetic factors in reaction to exposures
Antifertility and prenatal effects
|
