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CISDOC database

Document ID (ISN)19694
CIS number 72-2694
ISSN - Serial title 0003-4819 - Annals of Internal Medicine
Year 1971
Convention or series no.
Author(s) Coates E.O., Watson J.H.L.
Title Diffuse interstitial lung disease in tungsten carbide workers.
Bibliographic information Nov. 1971, Vol.75, p.709-716. Illus. 19 ref.
Abstract Case reports are given of 12 persons employed in the manufacture or grinding of tungsten carbide who developed a progressive diffuse interstitial pneumonia, characterised clinically by non-productive cough and by dyspnoea on exertion. Lung tissue examined by light microscopy in 8 patients and by electron microscopy in 1 showed interstitial infiltrates of mononuclear and mast cells, desquamated hystiocytes in the alveoli, and various amounts of interstitial fibrosis; 8 of the patients died. Details are given on observation of 5 additional subjects with episodic cough related to carbide dust exposure but without roentgen abnormalities. The disease is a pneumoconiosis caused by inhalation of finely powdered cobalt in the carbide formulation.
Descriptors (primary) tungsten carbide 1:1; powder metallurgy; cemented carbides; hard metal pneumoconiosis; pulmonary fibrosis
Descriptors (secondary) cobalt; progressive massive fibrosis; case study; lung biopsy; dyspnoea; respirable dust; tungsten
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Metalworking industry
Inorganic substances
Pneumoconioses