|Document ID (ISN)||19647|
|ISSN - Serial title
||0032-6291 - PracovnÝ lÚkařstvÝ
|Convention or series no.
||CramÚr K., Selander S.
||Comparison between D-penicillamine and N-acetyl-D-penicillamine in the treatment of lead poisoning
||Mar. 1972, Vol.24, No.2-3, p.46-48. Illus. 7 ref.
||D-Penicillamine and N-acetyl-D-penicillamine were compared in the treatment of 2 workers with excessive lead absorption. The acetylated compound did not produce any significant increase in urinary lead; the non-acetylated compound had a satisfactory chelating action and produced an immediate reduction in urinary concentration and 24-h elimination of δ-aminolevulinic acid. The existence of a free amino group is essential for the chelating of D-penicillamine.
||lead; chelation therapy; chronic poisoning; toxicology
||ALAD; urinary ala monitoring; shipbreaking; penicillamine
||D - Periodical articles
||Medicine, hygiene and first aid
|Broad subject area(s)
Lead and compounds