| Document ID (ISN) | 18805 |
| CIS number |
73-1310 |
| ISSN - Serial title |
0028-0836 - Nature |
| Year |
1973 |
| Convention or series no. |
|
| Author(s) |
Lloyd D.C. |
| Title |
Chromosome aberration dosimetry in a case of overexposure to radiation |
| Bibliographic information |
5 Jan. 1973, Vol.241, No.5384, p.69-70. 7 ref. |
| Abstract |
Description of a case where a radiation worker was referred to hospital with radiation injury to both hands after working for 3yrs with iridium-192 sources; 2yrs later the chromosome aberration technique was used to assess accumulated radiation dose, as he had continued in radiation work. From a blood sample lymphocyte cultures were made and 500 metaphase spreads were examined, with the following results: dicentrics, 49; centric rings, 7; acentric rings, 10; interstitial deletions, 31; terminal deletions, 21. It is claimed that studies of this kind illustrate the valuable contribution of chromosome analysis to radiological protection practice, espcially where there is a lack of reliable physical dosimetry data, as well as to the eventual evaluation of risk of the late effects of radiation in terms of acute biological effect. |
| Descriptors (primary) |
radioactive substances; personnel monitoring; chromosome changes; genetic effects |
| Descriptors (secondary) |
ionizing radiation; radiation protection; case study; iridium; irradiation; hand injuries; radiation injury; biological effects; blood cytology; analysis of chromosome aberrations; cytology; hazard evaluation |
| Document type |
D - Periodical articles |
| Subject(s) |
Radiation
|
| Broad subject area(s) |
Physical hazards
|
| Browse category(ies) |
Genetic factors in reaction to exposures
Antifertility and prenatal effects
|
