| Document ID (ISN) | 18790 |
| CIS number |
73-1135 |
| ISSN - Serial title |
0003-9896 - Archives of Environmental Health |
| Year |
1972 |
| Convention or series no. |
|
| Author(s) |
Stokinger H.E. |
| Title |
Concepts of thresholds in standards setting |
| Bibliographic information |
Sep. 1972, Vol.25, No.3, p.153-157. Illus. 5 ref. |
| Abstract |
A discussion of the premises on which the concept of threshold of toxicological response is based, confined to chemical substances in the air of workplaces, for which the threshold concept is represented by a non-linear relationship between dose and initial response. The metabolic factors governing toxicological response - particularly homeostasis and adaptation, are reviewed. The precautions to be observed in establishing threshold limit values for man in industry are discussed at some length (heterogeneity of the human species, synergistic factors - alcohol drinking, smoking, dietary habits, predisposing diseases, etc.). |
| Descriptors (primary) |
threshold limit values; determination of concentration; toxic substances; toxicology |
| Descriptors (secondary) |
toxic effects; airborne dust; metabolic process; alcoholism; dose-response relationship; harmful substances; diet; synergism; absorbed dose; smoking |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Nutrition
Occupational exposure limits
Alcohol and drug abuse
|
