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Document ID (ISN)18778
CIS number 73-1311
ISSN - Serial title 0003-9896 - Archives of Environmental Health
Year 1973
Convention or series no.
Author(s) Stewart R.D.
Title Experimental human exposure to high concentrations of carbon monoxide
Bibliographic information Jan. 1973, Vol.26, No.1, p.1-7. Illus. 9 ref.
Abstract Six human volunteers were exposed to various CO concentrations ranging from 1000ppm for 10min to 35,600ppm for 45s. The experimental procedure and the results are presented and discussed in detail (blood and breath analyses, subjective and cardiovascular responses, electroencephalographic records, visual evoked responses). CO was absorbed rapidly. It was found that the increase in percent carboxyhaemoglobin saturation in venous blood per litre of CO mixture inhaled can be accurately predicted by the equation log (Δ% COHb/L) = 1.036 log (ppm CO inhaled) - 4.4793.
Descriptors (primary) carbon monoxide; determination of concentration; inhalation
Descriptors (secondary) electroencephalographic changes; carboxyhaemoglobin level; experimental pathology; human experiments; experimental determination; prediction formulae; blood monitoring; cardiovascular diseases; description of technique; length of exposure
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Carbon monoxide
Inorganic substances