| Document ID (ISN) | 112440 |
| CIS number |
12-0239 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2011 |
| Convention or series no. |
|
| Author(s) |
Zhang L., Ye F.L., Chen T., Mei Y., Song S.Z. |
| Title |
Trans, trans-muconic acid as a biomarker of occupational exposure to high-level benzene in China |
| Bibliographic information |
Oct. 2011, Vol.53, No.10, p.1194-1198. Illus. 41 ref. |
| Internet access |
Trans_trans-muconic_acid_[BUY_THIS_ARTICLE] [in English]
ILO_LABORDOC_[INTRANET_ACCESS] [in English]
|
| Abstract |
The work aimed to study the potential correlation between high-level benzene exposures and urinary benzene metabolites S-phenylmercapturic acid (SPMA) and trans, trans-muconic acid (t,t-MA) among Chinese shoe industry workers. Individual benzene-exposed levels were determined by gas chromatography analysis; urinary metabolites were determined by high performance liquid chromatography coupled with mass spectrometry. The concentration of benzene ranged from 2.57 to 146.11 mg/m3. The correlation between benzene and t,t-MA was significantly higher than that of SPMA at the postshift. It is concluded that t,t-MA is a more specific biomarker than SPMA at high-level benzene exposures. |
| Descriptors (primary) |
China; benzene; trans,trans-muconic acid; exposure tests; shoe industry |
| Descriptors (secondary) |
determination in urine; exposure evaluation; reliability; description of technique |
| Document type |
D - Periodical articles |
| Subject(s) |
Leather, fur and footwear
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Aromatic hydrocarbons
Exposure evaluation
Footwear, leather and fur industry
|
