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Document ID (ISN)112311
CIS number 12-0227
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2011
Convention or series no.
Author(s) Fell A.K., Not° H., Skogstad M., Nordby K.C., Eduard W., Svendsen M.V., Ovsteb° R., Tr°seid A.M., Kongerud J.
Title A cross-shift study of lung function, exhaled nitric oxide and inflammatory markers in blood in Norwegian cement production workers
Bibliographic information Nov. 2011, Vol.68, No.11, p.799-805. Illus. 36 ref.
Internet access A_cross-shift_study_of_lung_function_[INTERNET_FREE_ACCESS] [in English]
Abstract The objective of this study was to evaluate possible effects of aerosol exposure on lung function, fractional exhaled nitric oxide (FeNO) and inflammatory markers in blood from Norwegian cement production workers across one work shift (0 to 8 h) and again 32 h after the non-exposed baseline registration. It involved 95 workers from two cement plants in Norway. Assessment of lung function included spirometry and gas diffusion pre- and post-shift. FeNO concentrations were measured and blood samples collected at 0, 8 and 32 h. Blood analysis included cell counts of leucocytes and mediators of inflammation. Findings are discussed. Overall, small cross-shift changes were observed in lung function and inflammatory markers among cement production workers, indicating that inflammatory effects may occur at exposure levels well below 1 mg/m3. However, the associations between these acute changes and personal exposure measurements were weak.
Descriptors (primary) nitric oxide; respirable dust; aerosols; pulmonary function; exposure evaluation; exposure tests; cement industry
Descriptors (secondary) Norway; fibrinogen; leukocytes; determination in blood; determination in exhaled air; blood count; spirometry
Document type D - Periodical articles
Subject(s) Materials, glass and ceramics
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Exposure evaluation
Cement and concrete