|Document ID (ISN)||112142|
|ISSN - Serial title
||1545-9624 - Journal of Occupational and Environmental Hygiene
|Convention or series no.
||Chang T.Y., Wang V.S., Lin S.Y., Yen H.Y., Lai J.S., Liu C.S.
||Co-exposure to noise, N,N-dimethylformamide, and toluene on 24-hour ambulatory blood pressure in synthetic leather workers
||Jan. 2010, Vol.7, No.1, p.14-22. 38 ref.
||Co-exposure_to_noise.pdf [in English]
||Independent exposures to noise, N,N-dimethylformamide (DMF) or toluene have been associated with cardiovascular effects, but the combined effects are not clear. This study investigated ambulatory systolic blood pressure (SBP) and diastolic blood pressure (DBP) in workers co-exposed to noise, DMF, and toluene. Twenty workers in a synthetic leather manufacturing company were recruited as study subjects. Personal noise exposure and ambulatory blood pressure were measured concomitantly for 24 h; airborne co-exposure to DMF and toluene during the working period was also analyzed to identify solvents exposure. Linear mixed-effects regressions were used to estimate effects on ambulatory blood pressure by controlling potential confounders. No significant differences in SBP and DBP were found between six high-solvent-exposure workers and office workers during any periods. After the Bonferroni correction, there were no significant differences in ambulatory blood pressure between high-exposure groups and the low-exposure groups. Our findings suggest no interactive effects of co-exposure to noise, DMF and toluene on workers' ambulatory blood pressure.
||noise; toluene; dimethylformamide; solvents; blood pressure; plastics converting industry
||Taiwan (China); statistical evaluation; synergism
||D - Periodical articles
||Chemicals, plastics and rubber
Toxic and dangerous substances
Noise, hearing and vibration
|Broad subject area(s)
||Occupational medicine, epidemiology