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Document ID (ISN)112142
CIS number 11-0796
ISSN - Serial title 1545-9624 - Journal of Occupational and Environmental Hygiene
Year 2010
Convention or series no.
Author(s) Chang T.Y., Wang V.S., Lin S.Y., Yen H.Y., Lai J.S., Liu C.S.
Title Co-exposure to noise, N,N-dimethylformamide, and toluene on 24-hour ambulatory blood pressure in synthetic leather workers
Bibliographic information Jan. 2010, Vol.7, No.1, p.14-22. 38 ref.
Internet access Co-exposure_to_noise.pdf [in English]
Abstract Independent exposures to noise, N,N-dimethylformamide (DMF) or toluene have been associated with cardiovascular effects, but the combined effects are not clear. This study investigated ambulatory systolic blood pressure (SBP) and diastolic blood pressure (DBP) in workers co-exposed to noise, DMF, and toluene. Twenty workers in a synthetic leather manufacturing company were recruited as study subjects. Personal noise exposure and ambulatory blood pressure were measured concomitantly for 24 h; airborne co-exposure to DMF and toluene during the working period was also analyzed to identify solvents exposure. Linear mixed-effects regressions were used to estimate effects on ambulatory blood pressure by controlling potential confounders. No significant differences in SBP and DBP were found between six high-solvent-exposure workers and office workers during any periods. After the Bonferroni correction, there were no significant differences in ambulatory blood pressure between high-exposure groups and the low-exposure groups. Our findings suggest no interactive effects of co-exposure to noise, DMF and toluene on workers' ambulatory blood pressure.
Descriptors (primary) noise; toluene; dimethylformamide; solvents; blood pressure; plastics converting industry
Descriptors (secondary) Taiwan (China); statistical evaluation; synergism
Document type D - Periodical articles
Subject(s) Chemicals, plastics and rubber
Toxic and dangerous substances
Noise, hearing and vibration
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Plastics industry
Cardiovascular diseases