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Document ID (ISN)112090
CIS number 11-0692
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2011
Convention or series no.
Author(s) Hung P.C., Cheng S.F., Liou S.H., Tsai S.W.
Title Biological monitoring of low-level 2-butoxyethanol exposure in decal transfer workers in bicycle manufacturing factories
Bibliographic information Oct. 2011, Vol.68, No.10, p.777-782. Illus. 36 ref.
Abstract In this study, exposures to 2-butoxyethanol (2-BE) in decal transfer workers in the Taiwan bicycle manufacturing industry were investigated. 80 workers in two bicycle factories completed a questionnaire. NIOSH method 1403 was adopted for air sampling and analysis of 2-BE. Pre-work and post-work urine samples were also collected for determination of total 2-butoxyacetic acid (BAA) after hydrolysis. Haemoglobin tests were performed using an automated haemoglobin analysis system. The 31 decal transfer workers whose hands were in direct contact with a dilute aqueous solution of 2-BE, were exposed to an average of 1.7 ppm of 2-BE in air. Correlation of 2-BE in air and postshift urinary BAA levels (after hydrolysis) was poor. Postshift total BAA levels in urine on Monday and Friday (446.8 and 619.4 mg/g creatinine) were around 223% and 310% of the ACGIH proposed Biological Exposure Index. Higher levels of total BAA were observed in the urine of subjects exposed to low-level 2-BE in air, presumably because of direct dermal contact. The mean pre-shift BAA on Friday was significantly higher than that on Monday, implying that the more days of exposures, the higher the accumulation. Since accumulation occurred with low-level exposure to 2-BE, it is recommended that urine samples be collected at the end of the working week.
Descriptors (primary) butoxyethanol; carcinogens; solvents; adhesives; exposure tests; bicycle industry
Descriptors (secondary) Taiwan (China); breathing atmosphere; determination in blood; determination in urine; exposure evaluation
Document type D - Periodical articles
Subject(s) Metal production and metalworking
Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Exposure evaluation
Metalworking industry