ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)111899
CIS number 11-0506
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2010
Convention or series no.
Author(s) Heck J.E., Charbotel B., Moore L.E., Karami S., Zaridze D.G., Matveev V., Janout V., Kollárová H., Foretova L., Bencko V., Szeszenia-Dabrowska N., Lissowska J., Mates D., Ferro G., Chow W.H., Rothman N., Stewart P., Brennan P., Boffetta P.
Title Occupation and renal cell cancer in Central and Eastern Europe
Bibliographic information Jan. 2010, vol.67, No.1, p.47-53. 42 ref.
Abstract Central and Eastern Europe has among the highest rates of renal cell cancer worldwide. Few studies have been conducted in these areas to investigate the possible role of occupational exposures in renal cell cancer aetiology. The purpose of this study was to examine the association of renal cell cancer with employment in specific occupations and industries. From 1999 to 2003, a hospital-based case-control study was conducted in seven areas of the Czech Republic, Poland, Romania and Russia. A detailed occupational history was collected from renal cell cancer cases and controls, together with information on potential confounders. Odds ratios (ORs) of cancer risk were calculated for having ever been employed in selected jobs and industries, with follow-up analyses examining duration of employment. A total of 992 histologically-confirmed incident renal cell cancer cases and 1459 controls were included in the analysis. An increased risk of renal cell cancer was observed for workers in agricultural labour and animal husbandry (OR 1.43), particularly among women employed as general farm workers (OR 2.73). Risk gradients for agricultural work increased with longer employment. An overall increased risk of renal cell cancer was seen among architects and engineers (OR 1.89), and mechanical engineers (OR 1.71).
Descriptors (primary) Eastern Europe; epidemiology; occupation disease relation; renal cancer; job-exposure relation; risk factors
Descriptors (secondary) Czech Republic; Poland; Romania; Russian Federation; diagnosis; length of service; histopathology; case-control study; statistical evaluation; length of exposure
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Cancer and carcinogens
Diseases of the kidney and the urinary system