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Document ID (ISN)111256
CIS number 10-0796
ISSN - Serial title 1077-3525 - International Journal of Occupational and Environmental Health
Year 2008
Convention or series no.
Author(s) van Larebeke N.A., Sasco A.J., Brophy J.T., Keith M.M., Gilbertson M., Watterson A.
Title Sex ratio changes as sentinel health events of endocrine disruption
Bibliographic information 2nd quarter 2008, Vol. 14, No.2, p.138-143. 77 ref.
Internet access Sex_ratio_changes.pdf [in English]
Abstract This review article on sex ratio changes as an early indicator of endocrine disruption presents the findings of recent epidemiological and mechanistic studies. The sex ratio in human populations can be readily measured to ascertain whether reproductive effects, such as subtle birth defects of the reproductive tract caused by exposures to chemicals, might be occurring. Male to female sex ratios appear to be declining in populations in several parts of the globe, possibly as a result of prenatal exposures to chemicals. Sex ratio data for communities with unusual occupational or environmental exposures can be compiled using traditional epidemiological techniques.
Descriptors (primary) epidemiology; harmful substances; sex-linked differences; endocrine effects
Descriptors (secondary) research; literature survey
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Biological hazards