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Document ID (ISN)111201
CIS number 10-0824
ISSN - Serial title 0944-2502 - Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie
Year 2010
Convention or series no.
Author(s) Mittmann-Frank M., Berger H., Pföhler C., Bücker A., Wilkens H., Arzt E., Schmitt K.P., Wennemuth G., Hannig M., Buchter A.
Title Exposure to nano particles and new materials - Clinical and diagnostic findings
Original title Klinische und diagnostische Befunde bei Exposition gegenüber Nanopartikeln und neuen Materialien [in German]
Bibliographic information Oct. 2010, Vol.60, No.10. p.328-348. Illus. 41 ref.
Internet access Klinische_und_diagnostische_Befunde.pdf [in German]
Abstract Ten individuals whose work involved long-term exposure to certain specific nanoparticles underwent detailed clinical examinations aimed at assessing individual factors and possible interactions caused by exposure to nanomaterials. Half the group showed a relevant obstructive ventilation disorder through particle inhalation before the introduction of protective measures. In three cases, computed tomography showed lung emphysema changes. Half the group showed a positive reaction to zirconium oxide. Analysis of biomarkers showed no evidence of respiratory tract inflammation. Implications of these and other findings are discussed. See also ISN 111203.
Descriptors (primary) nanoparticles; diagnosis; medical examinations; long-term exposure; health hazards; new technologies
Descriptors (secondary) zirconium oxide; sensitization; emphysema; obstructive ventilatory impairment; chest radiography; tomography
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Occupational pathology
Medicine, hygiene and first aid
Broad subject area(s) Chemical safety
New technologies
Browse category(ies) Nanotechnology and nanoparticles
Exposure evaluation
Diseases of the respiratory system (except for pneumoconiosis & similar)