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Document ID (ISN)110851
CIS number 10-0431
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 2010
Convention or series no.
Author(s) Puttonen S., Härmä M., Hublin C.
Title Shift work and cardiovascular disease - Pathways from circadian stress to morbidity
Bibliographic information Mar. 2010, Vol.36, No.2, p.96-108. Illus. 129 ref.
Internet access Shift_work_and_cardiovascular_disease.pdf [in English]
Abstract In order to establish a causal relation between shift work and cardiovascular disease (CVD), the pathways from the former to the latter need to be verified. This article reviews current knowledge of the mechanisms between shift work and CVD. Shift work can increase the risk of CVD by several interrelated psychosocial, behavioural, and physiological mechanisms. The psychosocial mechanisms relate to difficulties in controlling working hours, decreased work-life balance and poor recovery following work. The most probable behavioural changes are weight gain and smoking. The plausible physiological and biological mechanisms are related to the activation of the autonomic nervous system, inflammation, changed lipid and glucose metabolism, and related changes in the risk for atherosclerosis, metabolic syndrome and type II diabetes. The data provide evidence for possible disease mechanisms between shift work and CVD, but compelling evidence on any specific mechanism is missing.
Descriptors (primary) shift work; cardiovascular diseases; risk factors
Descriptors (secondary) hours of work; work time schedules; state of health; smoking; metabolic disturbances; diabetes mellitus; atherosclerosis; body weight; physiology; lipid metabolism; psychology of work organization; personal hygiene; biological effects; literature survey
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Physiology, ergonomics
Browse category(ies) Cardiovascular diseases
Psychology of work organization
Metabolic diseases
Endocrine diseases
Hours of work